The Fungal Pharmacology tool provides you with insight into possible pharmacokinetic interactions of antifungal agents and particular concomitant drugs, herbals and vitamins.
- Select antifungal drug.
- Search for concomitant drug by using the search field or search by drug class. Choosing a single drug, you can add other drugs by typing that name in the search field.
- Select concomitant drug from the list.
- Results are presented as A (no known interaction), B (no action needed), C (monitor therapy), D (consider therapy modification) and X (avoid combination) to indicate the recommendation along with a grading system of the evidence (very low, low, moderate, high).
- The interaction will provide you with information on the effect of the interaction, the recommended course of action, the probable underlying mechanism and a summary of literature with references.
- References are linked to the Product Information or PubMed citation.
- Additional information on the risk of QT prolongation is provided.
Alternative drugs from the same drug class can be selected at the bottom of the advice. Alternatives are given on class level. Whether the listed alternatives are a therapeutic alternative for the specific patient under the given circumstances, is the responsibility of the treating physician.
This tool is available free of charge and has been developed by the Fungal Pharmacology group at the Radboud University Medical Center, Nijmegen, the Netherlands trough support from Astellas Pharma, Gilead Sciences Inc., Merck Sharp & Dohme Corp. and Pfizer Inc..
The tool can be used on PC’s, laptops and tablets. The tool is compatible with Internet Explorer 8 and higher, Firefox, Chrome, and Safari.
For use on a smartphone, you can download the app.
Contact Fungal Pharmacology at: email@example.com.